Vaccine Preventability of Meningococcal Clone, Greater Aachen Region, Germany
نویسندگان
چکیده
منابع مشابه
Vaccine Preventability of Meningococcal Clone, Greater Aachen Region, Germany
Emergence of serogroup B meningococci of clonal complex sequence type (ST) 41/44 can cause high levels of disease, as exemplified by a recent epidemic in New Zealand. Multiplication of annual incidence rates (3.1 cases/100,000 population) of meningococcal disease in a defined German region, the city of Aachen and 3 neighboring countries (Greater Aachen) prompted us to investigate and determine ...
متن کاملEpidemiology of invasive meningococcal disease in Germany, 2002-2010, and impact of vaccination with meningococcal C conjugate vaccine.
OBJECTIVES To analyse serogroup (Sg)- and finetype-specific invasive meningococcal disease burden (IMD) in Germany, 2002-2010, with emphasis on effects of vaccination with conjugate SgC vaccines targeting one-year old children since 2006, including individual-based catch-up to 17 years of age. METHODS Serogroup- and age-specific IMD incidence and trends were calculated using statutory surveil...
متن کاملSpatiotemporal Analysis of Invasive Meningococcal Disease, Germany
Meningococci can cause clusters of disease. Specimens from 1,616 patients in Germany obtained over 42 months were typed by serogrouping and sequence typing of PorA and FetA and yielded a highly diverse dataset (Simpson's index 0.963). A retrospective spatiotemporal scan statistic (SaTScan) was applied in an automated fashion to identify clusters for each finetype defined by serogroup variable r...
متن کاملA new meningococcal B vaccine
Neisseria meningitidis is an important cause of invasive bacterial infection in children worldwide, and is a rare example of a bacterium that has evolved to become an obligate human commensal which commonly colonizes the oropharyngeal mucosa. Carriage is age-dependent and appears to be very common in young adults. The relationships between carriage and invasive disease are not completely unders...
متن کاملEffectiveness of meningococcal serogroup C vaccine programmes.
Since the introduction of monovalent meningococcal serogroup C (MenC) glycoconjugate (MCC) vaccines and the implementation of national vaccination programmes, the incidence of MenC disease has declined markedly as a result of effective short-term vaccination and reduction in acquisition of MenC carriage leading to herd protection. Monovalent and quadrivalent conjugate vaccines are commonly used...
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ژورنال
عنوان ژورنال: Emerging Infectious Diseases
سال: 2010
ISSN: 1080-6040,1080-6059
DOI: 10.3201/eid1603.091102